Takotsubo Cardiomyopathy – More than 30 years after its description. Case report and literature review
Abstract
Takotsubo Cardiomyopathy is an acute heart disease with a clinical presentation similar to acute coronary syndrome. It mainly affects postmenopausal women, often preceded by emotional or physical stress. Patients with predisposing factors such as malignancy and chronic comorbidities are more likely to suffer from this syndrome. The pathogenesis is unclear and have been proposed as mechanisms: coronary spasm, microvascular dysfunction, aborted myocardial infarction, obstruction of the left ventricular outflow tract, myocardial toxicity due to catecholamines, and autonomic dysfunction. But until now it has not been possible to establish with clarity the exact cause of this pathology. The case of a postmenopausal woman with initial diagnosis of Acute Coronary Syndrome is described. In the coronary angiography, no significant lesions were found, and in the ventriculography the apical abalonation was observed, which is characteristic of this syndrome. In this case there was a complete recovery of the patient. More research is needed to try to elucidate clearly the pathophysiology of this syndrome and thus, try to protocolize a management to have a targeted therapy that achieves a faster recovery, without sequelae and a better prognosis in our patients.
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Disciplines:
Cardiology, Internal MedicineReferences
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