Successful of therapeutic hypothermia intervention in newborn with hypoxic-ischemic encephalopathy. A case report
Abstract
Perinatal encephalopathy hypoxic-ischemic (HIE) moderate-severe is a disease with a high risk of mortality and morbidity. Hypothermia is a neuroprotective therapy useful improving the prognosis in term newborns with HIE. This is a case report at Neiva Huila of a newborn who suffered severe perinatal HIE and got hypothermia therapy. Neurological evaluation, three months after treatment, showed an adequate tone and suction. In this case, hypothermia therapy was an effective measure for treatment of HIE, it could decrease mortality and neurological damage.Downloads
References
Patel SD, Pierce L, Ciardiello AJ, Vannucci SJ. Neonatal encephalopathy: pre-clinical studies in neuroprotection. Biochem Soc Trans. 2014;42(2):564-8.
Shankaran S. Outcomes of hypoxic-ischemic encephalopathy in neonates treated with hypothermia. Clin Perinatol. 2014;41(1):149-59.
Jacobs SE, Berg M, Hunt R, Tarnow-Mordi WO, Inder TE, Davis PG. Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev. 2013(1):Cd003311.
Jacobs SE, Morley CJ, Inder TE, Stewart MJ, Smith KR, McNamara PJ, et al. Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: a randomized controlled trial. Arch Pediatr Adolesc Med. 2011;165(8):692-700.
Martinez-Biarge M, Blanco D, Garcia-Alix A, Salas S. [Follow-up of newborns with hypoxic-ischaemic encephalopathy]. An Pediatr (Barc). 2014;81(1):52.e1-14.
Drury PP, Gunn ER, Bennet L, Gunn AJ. Mechanisms of hypothermic neuroprotection. Clin Perinatol. 2014;41(1):161-75.
Chalak LF, Sanchez PJ, Adams-Huet B, Laptook AR, Heyne RJ, Rosenfeld CR. Biomarkers for severity of neonatal hypoxic-ischemic encephalopathy and outcomes in newborns receiving hypothermia therapy. J Pediatr. 2014;164(3):468-74.e1.
Beken S, Aydin B, Dilli D, Erol S, Zenciroglu A, Okumus N. Can biochemical markers predict the severity of hypoxic-ischemic encephalopathy? Turk J Pediatr. 2014;56(1):62-8.
Perez A, Ritter S, Brotschi B, Werner H, Caflisch J, Martin E, et al. Long-term neurodevelopmental outcome with hypoxic-ischemic encephalopathy. J Pediatr. 2013;163(2):454-9.
Thoresen M. Hypothermia after perinatal asphyxia: selection for treatment and cooling protocol. J Pediatr. 2011;158(2 Suppl):e45-9.
Zanelli S, Buck M, Fairchild K. Physiologic and pharmacologic considerations for hypothermia therapy in neonates. J Perinatol. 2011;31(6):377-86.
Azzopardi D, Strohm B, Marlow N, Brocklehurst P, Deierl A, Eddama O, et al. Effects of hypothermia for perinatal asphyxia on childhood outcomes. N Engl J Med. 2014;371(2):140-9.
.png)
